ADVANCED GLYCATION END-PRODUCT PRECURSOR METHYLGLYOXAL MAY LEAD TO DEVELOPMENT OF ALZHEIMER’S DISEASE


Insights into semi-continuous synthesis of iron oxide nanoparticles (IONPs) via thermal decomposition of iron oleate

Abstract The increasing demand for magnetic iron oxide nanoparticles (IONPs) in biomedicine necessitates efficient and scalable production methods.Thermal decomposition offers excellent tailoring Saddle Bags of the particle properties but its discontinuous batch-operation is restricting scale-up and industrial application.To overcome these challeng

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Subcellular drug targeting illuminates local kinase action

Deciphering how signaling enzymes operate within discrete microenvironments is fundamental to understanding biological processes.A-kinase anchoring proteins (AKAPs) restrict the range of action of protein kinases within intracellular compartments.We exploited the AKAP targeting concept to create genetically encoded platforms that restrain kinase in

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